6. Does my skin change with my cycle?

TL;DR: The skin can change as hormones rise and fall during the menstrual cycle. However, the degree of change varies a lot from person to person.

Research: While research understands the mechanisms through which hormones can affect skin, studies on these changes in real-life settings are limited. Three reviews show that changes in estrogen, progesterone, and androgens during the menstrual cycle can affect the skin in many ways. However, researchers note that current evidence is limited and inconsistent.1 2 3

Doc’s opinion: Skin responds to hormones. It may appear the best around ovulation when estrogen peaks. Then, in the luteal phase, as estrogen declines and progesterone rises, skin may become oily and acne-prone.

However, the severity of the skin changes varies for everyone, based on hormone sensitivity, genetics, lifestyle, and underlying health conditions.

Managing hormone-related skin changes is possible. Some actions must be taken in the luteal phase (e.g., using an oil-control face wash, reducing sugar), and some throughout the cycle (e.g., using a gentle cleanser, having low-glycemic and anti-inflammatory foods, ensuring specific micronutrients).

What we know

Relationship between skin and hormones

The skin is the largest organ in the body. It comprises many layers. The outermost layer (epidermis) and middle layer (dermis) have hormone receptors. This means the skin can receive and respond to signals from various hormones, including sex hormones that regulate the menstrual cycle.4

Here is a quick overview of how sex hormones influence overall skin health.

Hormone
What skin functions it controls

Estrogen5

  • Oil production: Decreases oil production by suppressing the sebaceous (oil) gland activity

  • Collagen production: Maintain skin thickness, elasticity, and structure

  • Hydration: Boosts skin moisture

  • Skin barrier function: Makes skin less sensitive and reactive to irritants, helping prevent inflammation

  • Wound healing: Supports repair of damaged skin

  • Pigmentation: Regulates pigment production

  • Skin blood flow: Improves circulation to deliver nutrients and oxygen; regulates temperature, immunity, and healing

Progesterone6

  • Oil production: Increases oil production by stimulating the sebaceous (oil) gland activity

  • Skin barrier function: Makes skin more reactive to irritants, which can increase sensitivity and inflammation

  • Skin temperature7: Raises skin temperature

  • Sweating: Increases perspiration

Androgens8

  • Oil production: Triggers the sebaceous gland, contributing to increased oil production

Possible effects of hormonal changes during the menstrual cycle on the skin

Sex hormones directly affect your skin. So, their fluctuations throughout the menstrual cycle may lead to various skin changes.

Note: The breakdown of phases below is based on a typical 28-day cycle. While the cycle length can be shorter or longer, the phases follow the same order and timing. For example, ovulation usually happens around the middle of the cycle, which is day 14 in a 28-day cycle and day 16 in a 32-day cycle.

MENSTRUAL/ EARLY FOLLICULAR PHASE (1-5 DAYS)

Hormonal changes: Low estrogen and progesterone

What may happen to your skin: Dry, dull, and sensitive skin9; flare-ups may continue

Why it happens:

  • Low hydration and collagen

  • Weak skin barrier function

MID FOLLICULAR PHASE (6-10 DAYS)

Hormonal changes: High estrogen, low progesterone

What may happen to your skin: Smoother, more radiant skin5

Why it happens:

  • Increased collagen and hydration

  • Stronger skin barrier function

  • Improved wound healing and repair

LATE FOLLICULAR PHASE (11-13 DAYS)

Hormonal changes: High estrogen and androgens, low progesterone

What may happen to your skin: Healthy-looking skin5

Why it happens:

  • Enhanced skin blood flow

  • Slight increase in oil production

OVULATION (AROUND DAY 14)

Hormonal changes: Peak estrogen

What may happen to your skin: Skin looks its best—firm, smooth, and glowing5

Why it happens:

  • Improved skin elasticity

EARLY & MID LUTEAL PHASE (15-23 DAYS)

Hormonal changes: High progesterone, moderate estrogen

What may happen to your skin: Oilier skin6, higher skin temperature, sweating7

Why it happens:

  • Rise in oil production

  • Higher than usual skin blood flow

LATE LUTEAL/ PREMENSTRUAL PHASE (24-28 DAYS)

Hormonal changes: Declining progesterone and estrogen

What may happen to your skin: Sensitivity, breakouts, worsening of existing skin conditions such as acne10, dermatitis11, eczema, and psoriasis2

Why it happens:

  • Weakest skin barrier function

  • Peak oiliness

Does everyone experience skin changes during the menstrual cycle?

The short answer is yes. However, the severity and visibility of skin changes depend on several factors.

  1. Hormone sensitivity12

How strongly the skin responds to fluctuations in estrogen, progesterone, and androgens during the menstrual cycle varies from person to person. This sensitivity can be influenced by the immune system, environmental triggers, and certain medications. If you are highly sensitive, you may experience more noticeable symptoms, such as:

  • Dermatitis (skin inflammation)

  • Pruritus (itching)

  • Acne

  1. Genetics13

Genes and hormone-related skin changes are connected. Specific genes influence skin functions like:

  • Sebaceous (oil) gland activity

  • Inflammation

  • Hydration

  • Barrier function (protecting the skin from irritants or allergens)

Carrying certain gene variants may make you prone to oily skin and acne, particularly in response to hormonal changes during the cycle.

  1. Lifestyle and diet factors

A few lifestyle and diet can also intensify skin changes during the cycle:

  • Stress: Stress increases a hormone called cortisol in the body. It worsens skin inflammation, itching, oil production, barrier function, wound healing, and immunity. As a result, stress can aggravate skin conditions such as acne, dermatitis, and psoriasis.14

  • Sleep: Poor sleep quality and deprivation can reduce skin barrier function, hydration, and elasticity.15 16

  • Hydration: Dehydration can impair skin barrier function, making skin more reactive to hormones.17

  • Diet: High-glycemic-index foods18 (e.g., white bread, breakfast cereals, and savoury snacks) can trigger or worsen acne. Foods that cause inflammation, like processed meats, refined sugars, and certain dairy products (e.g., skimmed milk), can worsen dermatitis and psoriasis.19

  1. Polycystic ovary syndrome (PCOS)

Women with PCOS have high levels of androgens, which increase oil production. It can lead to persistent and more severe acne during the cycle.20

A doc’s guide: How to manage skin changes during your cycle

A simple skincare routine, a healthy diet, and lifestyle changes can help you manage hormone-related skin changes. Here’s a doctor-backed checklist to support your skin throughout the cycle:

Skincare routine

Diet

Lifestyle

  • Aerobic exercise (e.g., walking, cycling): Improves circulation, oxygen delivery, and waste removal.

  • Strength training (e.g., bodyweight exercises, weight lifting): Encourages collagen production and helps maintain skin firmness.

  • Yoga and Pilates: Reduce stress hormones like cortisol, which can aggravate skin conditions like acne.

Note: Overexercising can cause dehydration and elevated cortisol levels, making the skin dry and worsening flare-ups. Be sure to include recovery days in your weekly exercise routine.

References
  1. Nguyen ML, Nguyen S, Sood N, Marivada S, Magaldino A, Mayrovitz HN. Physiological Changes in Women’s Skin During the Menstrual Cycle: A Scoping Review. Cureus. 2024 Dec 7;16(12).

  2. Raghunath RS, Venables ZC, Millington GW. The menstrual cycle and the skin. Clinical and experimental dermatology. 2015 Mar 1;40(2):111-5.

  3. Palaniappan V, Gopinath H, Murthy AB, Gupta A, Karthikeyan K. A narrative review of Catamenial dermatology: A glimpse into the menstrual symphony. Indian Journal of Dermatology, Venereology and Leprology.:1-1.

  4. Zouboulis CC. The human skin as a hormone target and an endocrine gland. HORMONES-ATHENS-. 2004 Jan 1;3:9-26.

  5. Shah MG, Maibach HI. Estrogen and skin: an overview. American journal of clinical dermatology. 2001 Jun;2(3):143-50.

  6. Stephens CJ. Perimenstrual eruptions. Clinics in dermatology. 1997 Jan 1;15(1):31-4.

  7. Charkoudian N, Stephens DP, Pirkle KC, Kosiba WA, Johnson JM. Influence of female reproductive hormones on local thermal control of skin blood flow. Journal of Applied Physiology. 1999 Nov 1;87(5):1719-23.

  8. Muizzuddin N, Marenus KD, Schnittger SF, Sullivan M, Maes DH. Effect of systemic hormonal cyclicity on skin. International Journal of Cosmetic Science. 2006 Feb;28(1):77-.

  9. Geller L, Rosen J, Frankel A, Goldenberg G. Perimenstrual flare of adult acne. The Journal of clinical and aesthetic dermatology. 2014 Aug;7(8):30.

  10. Kiriyama K, Sugiura H, Uehara M. Premenstrual deterioration of skin symptoms in female patients with atopic dermatitis. Dermatology. 2003 Mar 10;206(2):110-2.

  11. Itsekson AM, Seidman DS, Zolti M, Alesker M, Carp HJ. Steroid hormone hypersensitivity: clinical presentation and management. Fertility and sterility. 2011 Jun 30;95(8):2571-3.

  12. Heng AH, Say YH, Sio YY, Ng YT, Chew FT. Gene variants associated with acne vulgaris presentation and severity: a systematic review and meta-analysis. BMC medical genomics. 2021 Apr 13;14(1):103.

  13. Chen Y, Lyga J. Brain-skin connection: stress, inflammation and skin aging. Inflammation & Allergy-Drug Targets (Formerly Current Drug Targets-Inflammation & Allergy)(Discontinued). 2014 Jun 1;13(3):177-90.

  14. Jang SI, Lee M, Han J, Kim J, Kim AR, An JS, Park JO, Kim BJ, Kim E. A study of skin characteristics with long‐term sleep restriction in Korean women in their 40s. Skin research and technology. 2020 Mar;26(2):193-9.

  15. Oyetakin‐White P, Suggs A, Koo B, Matsui MS, Yarosh D, Cooper KD, Baron ED. Does poor sleep quality affect skin ageing?. Clinical and experimental dermatology. 2015 Jan 1;40(1):17-22.

  16. Verdier‐Sévrain S, Bonté F. Skin hydration: a review on its molecular mechanisms. Journal of cosmetic dermatology. 2007 Jun;6(2):75-82.

  17. Atkinson FS, Brand-Miller JC, Foster-Powell K, Buyken AE, Goletzke J. International tables of glycemic index and glycemic load values 2021: a systematic review. The American journal of clinical nutrition. 2021 Nov 1;114(5):1625-32.

  18. Afvari S, Beck TC, Kazlouskaya M, Afrahim R, Valdebran M. Diet, sleep, and exercise in inflammatory skin diseases. Our dermatology online. 2023;14(4):430.

  19. Lee AT, Zane LT. Dermatologic manifestations of polycystic ovary syndrome. American journal of clinical dermatology. 2007 Aug;8(4):201-19.

Vaibhavi Kodnani

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